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Dinner / Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce
Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce

Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce

October 19, 2025 von Arla Williams

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Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce is a delightful dish that combines tender chicken with creamy, cheesy pasta. This recipe is perfect for family dinners or special occasions, offering a rich flavor profile that will impress any guest. The unique blend of spices adds a kick, making it an exciting meal for those who love bold flavors.

Why You’ll Love This Recipe

  • Delicious Flavor: The combination of garlic, Cajun seasoning, and three types of cheese creates a mouthwatering sauce that perfectly coats the pasta.
  • Easy to Prepare: With straightforward steps, this dish can be made quickly even on busy weeknights.
  • Versatile Dish: Serve it as a main course or as a side at gatherings; it’s sure to please everyone at the table.
  • Comfort Food: This creamy pasta dish is the ultimate comfort food, perfect for cozy nights in.
  • Customizable: Feel free to adjust the spice levels or add your favorite vegetables to make it your own.

Tools and Preparation

Before you begin cooking, gather your tools to ensure a smooth process.

Essential Tools and Equipment

  • Large pot for boiling pasta
  • Skillet
  • Measuring spoons and cups
  • Wooden spoon or spatula
  • Knife and cutting board

Importance of Each Tool

  • Large pot for boiling pasta: Ensures even cooking of the twisted pasta until al dente.
  • Skillet: Ideal for searing chicken and making the creamy sauce simultaneously, enhancing flavor.
  • Measuring spoons and cups: Provide accurate measurements for consistent results in your cooking.
Garlic

Ingredients

For the Chicken

  • 2 large boneless, skinless chicken breasts, cut into strips
  • 1 cup grated Parmesan cheese, for coating the chicken

For the Pasta

  • 12 oz twisted pasta, gemelli or fusilli recommended

For the Sauce

  • 4 tbsp unsalted butter, divided
  • 4 cloves garlic, minced
  • 1 tsp Cajun seasoning
  • 1 tsp smoked paprika
  • Salt and black pepper, to taste
  • 1 cup heavy cream
  • 1 cup low-sodium chicken broth
  • 1 cup shredded mozzarella cheese
  • 1 cup shredded cheddar cheese
  • ½ cup grated Parmesan cheese, for sauce
  • 2 oz cream cheese, softened
  • 1 tsp Italian seasoning
  • 1 tsp dried basil
  • ½ tsp crushed red pepper flakes, optional
  • Fresh parsley or dried herbs, for garnish

How to Make Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce

Step 1: Boil the Pasta

Boil a large pot of salted water. Cook your twisted pasta until al dente. Drain it well and set aside.

Step 2: Prepare the Chicken

Season chicken strips with Cajun seasoning, smoked paprika, salt, and pepper. Press grated Parmesan into the chicken to create a light cheesy crust.

Step 3: Sear the Chicken

Heat olive oil and 2 tablespoons of butter in a large skillet over medium-high heat.
– Add the seasoned chicken strips.
– Sear them for about 5-7 minutes, turning occasionally until golden brown and cooked through.
– During the last minute of cooking, add 1 tablespoon of butter and half of the minced garlic. Let it sizzle before removing from heat.

Step 4: Make the Sauce

In the same skillet:
– Melt the remaining tablespoon of butter.
– Add the rest of the minced garlic and sauté for approximately 30 seconds until fragrant.
– Pour in heavy cream and chicken broth; stir well before bringing to a simmer.

Step 5: Add Cheeses

  • Incorporate softened cream cheese into the sauce and whisk until smooth.
  • Gradually stir in mozzarella, cheddar, and Parmesan cheeses until thickened.

Step 6: Seasoning

Season your sauce with Italian seasoning, dried basil, and crushed red pepper flakes if desired. Adjust salt and pepper to taste.

Step 7: Combine Pasta with Sauce

Add cooked twisted pasta into your creamy sauce. Toss gently until every piece is coated. Let it simmer on low heat for about 12 minutes so that flavors mingle beautifully.

Step 8: Serve

Plate your cheesy pasta generously topped with garlic Parmesan chicken strips. Garnish with fresh parsley or dried herbs for an extra touch!

Enjoy your flavorful Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce!

How to Serve Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce

Serving Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce can enhance the dining experience. Here are some creative ways to present and enjoy this delicious dish.

With Fresh Herbs

  • Chopped Parsley: Sprinkle freshly chopped parsley over the dish for a pop of color and flavor.
  • Basil Leaves: Add whole basil leaves on top for a fragrant touch that complements the sauce.

Accompanied by Breads

  • Garlic Bread: Serve with warm garlic bread for a crunchy, buttery contrast to the creamy pasta.
  • Breadsticks: Soft, cheesy breadsticks make perfect dippers for leftover sauce.

With a Side Salad

  • Caesar Salad: A classic Caesar salad provides a crisp, refreshing balance to the rich pasta.
  • Garden Salad: A simple garden salad with mixed greens and vinaigrette can lighten up the meal.

In Individual Portions

  • Personal Bowls: Serve in individual bowls for an elegant presentation at gatherings or dinner parties.
  • Mason Jars: Layering the pasta in mason jars can create a fun and portable option for picnics or lunch.

How to Perfect Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce

Perfecting this recipe is all about attention to detail. Here are some tips to elevate your dish.

  • Use Fresh Ingredients: Fresh garlic and quality cheeses make a significant difference in flavor.
  • Cook Pasta Al Dente: Ensure you cook the twisted pasta just right; it should have a slight bite for optimal texture when mixed with the sauce.
  • Adjust Spice Levels: Modify the amount of Cajun seasoning and crushed red pepper flakes according to your heat preference.
  • Whisk the Sauce Thoroughly: Whisking helps achieve a smooth and creamy texture, preventing lumps from forming.
  • Let It Simmer: Allowing the pasta to simmer in the sauce enhances flavor absorption, making every bite delicious.
  • Garnish Creatively: Don’t just stop at parsley; try adding shaved cheese or toasted breadcrumbs for added texture.

Best Side Dishes for Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce

Pairing side dishes with Garlic Parmesan Chicken Twisted Pasta can elevate your meal experience. Here are some great options that complement this dish beautifully.

  1. Steamed Broccoli: A simple side of steamed broccoli adds nutrition and balances out the richness of the pasta.
  2. Roasted Asparagus: Roasted asparagus drizzled with olive oil brings out its natural flavors while adding a nice crunch.
  3. Caprese Salad: This fresh salad of tomatoes, mozzarella, and basil offers a light, refreshing contrast to the creamy sauce.
  4. Grilled Zucchini: Lightly seasoned grilled zucchini is not only healthy but also adds a smoky flavor that pairs well with pasta.
  5. Corn on the Cob: Sweet corn on the cob makes for a delightful side that’s both fun to eat and deliciously sweet.
  6. Coleslaw: A tangy coleslaw can bring crunch and acidity, balancing out the heaviness of the dish nicely.
  7. Crusty Artisan Bread: Serve slices of crusty artisan bread for soaking up any leftover sauce on your plate.
  8. Stuffed Bell Peppers: Colorful stuffed bell peppers filled with grains or veggies offer an appealing presentation alongside your pasta dish.

Common Mistakes to Avoid

Cooking can be tricky, and it’s easy to make errors. Here are some common mistakes to avoid when making Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce.

  • Skipping the seasoning – Not seasoning your chicken properly can lead to bland flavors. Ensure you generously apply Cajun seasoning and salt before cooking.
  • Overcooking the pasta – Cooking pasta for too long will make it mushy. Aim for al dente, which means firm but not hard, so it holds up well with the sauce.
  • Not letting the sauce simmer – Rushing through the simmering process can prevent the flavors from developing. Let the sauce cook on low heat for at least 12 minutes.
  • Using cold cream cheese – Adding cold cream cheese can cause clumping in the sauce. Soften it first by leaving it out or microwaving it briefly.
  • Neglecting to garnish – Skipping the garnish may lead to a less appealing dish. A sprinkle of parsley adds color and freshness, enhancing presentation.

Storage & Reheating Instructions

Refrigerator Storage

  • item Store in an airtight container.
  • item Can be kept for up to 3 days in the fridge.

Freezing Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce

  • item Freeze in a freezer-safe container or bag.
  • item Best consumed within 2 months for optimal flavor.

Reheating Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce

  • Oven – Preheat to 350°F (175°C), cover with foil, and heat for about 20 minutes or until warmed through.
  • Microwave – Heat in a microwave-safe dish for 1–2 minutes, stirring halfway through for even heating.
  • Stovetop – Warm over medium heat with a splash of broth or water to help loosen the sauce as you stir.

Frequently Asked Questions

Here are some frequently asked questions about Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce.

Can I use different types of pasta?

Yes! You can use any twisty shape like gemelli or fusilli, depending on your preference or what you have on hand.

What if I don’t have Cajun seasoning?

You can make your own by combining paprika, cayenne pepper, garlic powder, onion powder, and dried herbs for a similar flavor profile.

Can I make this dish vegetarian?

Absolutely! Substitute chicken with sautéed vegetables like bell peppers and zucchini and use vegetable broth instead of chicken broth.

How spicy is the Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce?

The spiciness largely depends on how much crushed red pepper flakes you add. Adjust according to your taste preferences!

Final Thoughts

Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce is a delightful dish that balances creamy textures with zesty flavors. It’s versatile enough for customization—swap proteins or add vegetables as desired. Try this recipe today for a comforting meal that everyone will love!

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Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce

Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce

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Indulge in the rich and creamy goodness of Garlic Parmesan Chicken Twisted Pasta in Spicy Three-Cheese Cajun Sauce. This delightful dish pairs tender chicken with twisted pasta, all enveloped in a velvety sauce made from three types of cheese, garlic, and zesty Cajun seasonings. Perfect for family dinners or special occasions, this recipe delivers bold flavors that will impress your guests. Easy to prepare and customizable, you can adjust the spice level or add your favorite vegetables to suit your taste. Enjoy this comforting dish that is sure to become a household favorite!

  • Total Time: 45 minutes
  • Yield: Serves 4

Ingredients

Scale
  • 2 large boneless, skinless chicken breasts
  • 12 oz twisted pasta (gemelli or fusilli)
  • 4 tbsp unsalted butter
  • 4 cloves garlic
  • 1 tsp Cajun seasoning
  • 1 tsp smoked paprika
  • Salt and black pepper to taste
  • 1 cup heavy cream
  • 1 cup low-sodium chicken broth
  • 1 cup shredded mozzarella cheese
  • 1 cup shredded cheddar cheese
  • ½ cup grated Parmesan cheese
  • 2 oz cream cheese, softened
  • 1 tsp Italian seasoning
  • 1 tsp dried basil
  • ½ tsp crushed red pepper flakes, optional
  • Fresh parsley or dried herbs for garnish

Instructions

  1. Boil salted water in a large pot and cook twisted pasta until al dente. Drain and set aside.
  2. Season chicken strips with Cajun seasoning, smoked paprika, salt, and pepper. Press grated Parmesan onto the chicken.
  3. Heat olive oil and 2 tablespoons of butter in a skillet over medium-high heat. Sear the chicken strips for about 5-7 minutes until golden brown.
  4. In the same skillet, melt remaining butter, sauté minced garlic for about 30 seconds, then add heavy cream and chicken broth; simmer.
  5. Whisk in softened cream cheese until smooth; gradually stir in mozzarella, cheddar, and Parmesan until thickened.
  6. Season sauce with Italian seasoning and crushed red pepper flakes if desired. Combine cooked pasta with sauce; simmer on low for about 12 minutes.
  7. Serve topped with garlic Parmesan chicken strips and garnish as desired.
  • Author: Emma Moyer
  • Prep Time: 15 minutes
  • Cook Time: 30 minutes
  • Category: Dinner
  • Method: Stovetop
  • Cuisine: American

Nutrition

  • Serving Size: 1 plate (approximately 340g)
  • Calories: 675
  • Sugar: 3g
  • Sodium: 780mg
  • Fat: 40g
  • Saturated Fat: 23g
  • Unsaturated Fat: 15g
  • Trans Fat: 0g
  • Carbohydrates: 47g
  • Fiber: 2g
  • Protein: 37g
  • Cholesterol: 160mg

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